- AproDerm® Emollient Cream is free from SLS, parabens, chlorocresol, fragrances and colours, these excipients are recognised potential irritants and sensitisers, as listed by MIMS2, which can be found in many creams. They can aggravate already sensitive skin which is why such excipients are absent from AproDerm® Emollient Cream hence it can be considered that the risk of a reaction to a patient will be greatly reduced thus aiding compliance.
An irritant is a substance that causes inflammation to the body in a non-immune way and can affect anyone who comes into contact with sufficient amounts of it for long enough, however those with atopic eczema are more sensitive to irritants. The skin can react straight away (immediate response) or after a period of repeated exposure. Irritants remove moisture (by affecting Natural Moisturising Factor) and oils from the outer skin layer allowing pathogens, irritants and allergens to enter the skin causing inflammation and further damage.
A skin sensitiser is a chemical that will cause an allergic reaction when exposed to the skin and, unlike an irritant, it will only affect those who are allergic to it. The initial exposure will not cause a reaction but continued exposure can and once a person has been sensitised to a product, contact with even a small amount of it will cause a reaction. The two conditions allergic and irritant dermatitis may coexist.
Symptoms typically seen include skin which can be red, swollen, blistered, dry, thickened, intensely itchy and cracked depending on whether the reaction is acute or chronic.
For a list of potential sensitisers found in emollients click here
The table below compares AproDerm® Emollient Cream against similar emollient creams
Table 1: Comparison of Aproderm® Emollient Cream with similar prescribed emollient products4